Treatment guide

Profhilo in London

Profhilo in London, editorial image
In short

What is Profhilo and what does it do?

Profhilo is a brand of stabilised hyaluronic acid injected at a small number of set points to improve skin hydration, firmness and quality. It is not designed to add volume or change shape. It is usually given as two sessions four weeks apart, with results developing over the following weeks.

ClassificationMedical device. Hyaluronic acid, stabilised without conventional chemical cross-linking
PurposeSkin quality, hydration and firmness. Not volume and not contour
ProtocolTwo sessions, four weeks apart, then maintenance
TechniqueA small number of defined injection points per side, then the product spreads
AreasFace, neck, décolletage, hands, inner arms
ResultDevelops over weeks. Assessed at around eight weeks from the first session
DurationCommonly around six months before maintenance

What bio-remodelling means in practice

Conventional dermal fillers are cross-linked so that they resist breakdown and hold a shape. Products in this category are stabilised differently, so that instead of staying where they are placed they spread through the tissue plane. The intention is not to occupy space but to hydrate the tissue and to stimulate the cells that produce collagen and elastin.

That difference explains everything about how the treatment behaves. It is injected at a handful of points rather than shaped by hand. It produces no immediate change in contour. And the result, when it comes, is a change in the quality and light of the skin rather than in its shape.

It is closer to a skin treatment delivered by needle than to a filler.

Who it suits

  • Skin that has become dull, thin or crepey rather than volume-depleted.
  • The neck and décolletage, where resurfacing carries more risk and heals more slowly.
  • Hands, where thinning skin shows tendons and vessels.
  • People who want an improvement in skin quality without downtime or a change in shape.
  • People who have been advised, correctly, that their concern is not a filler problem.

It suits less well:

  • Anyone hoping for a lift, a contour change or an obvious visible transformation.
  • Significant skin laxity, which this does not treat.
  • Deep static lines, which need a different approach.
  • People wanting a result before an event next week.
Naming a product

This page names a brand because the treatment is widely known by it and because the product is a medical device rather than a prescription-only medicine, so the advertising restrictions that apply to botulinum toxin do not apply here. Several comparable products exist. Ask what is being used and why.

The protocol and why it matters

The standard approach is two treatments four weeks apart. That interval is part of the protocol rather than a scheduling convenience, and skipping the second session generally means an underwhelming result.

Product is placed at a small number of defined points chosen to sit away from significant vessels and to allow even spread. Each point produces a small raised bleb which settles within hours. The technique is standardised, which is unusual in this field, but the assessment of whether you are a candidate is not.

  • Session one: injections, small blebs, settled within a few hours.
  • Weeks one to four: gradual improvement in hydration and light reflection.
  • Session two at four weeks.
  • Weeks four to eight: the meaningful change in firmness and texture.
  • Assessment at around eight weeks from the first session.
  • Maintenance, commonly around every six months.

Realistic results

The change is real and it is subtle. Skin looks better hydrated, reflects light more evenly, and feels firmer. Fine crepiness improves. People often report that others notice they look well without identifying why.

What does not happen: contour does not change, folds do not disappear, and skin that is genuinely lax does not tighten. Photographs promising dramatic lifting from this category of treatment should be treated with scepticism, and the treatment judged on what it is actually designed to do.

Risks and aftercare

  • Small raised blebs at each point, settling within a few hours.
  • Bruising at injection points.
  • Tenderness for a day.
  • Rarely, a nodule that persists, which needs assessment.
  • As with any injectable, infection is possible and vascular complications, while unlikely with this technique and product, are not impossible.

Standard aftercare: no make-up on the points for the rest of the day, no strenuous exercise, sauna or steam for around twenty four hours, no facials or massage over the area for two weeks, and do not press or massage the blebs. See the aftercare page.

How it fits with other treatments

This category works well alongside treatments that address different findings. Muscle treatment addresses movement, structural filler addresses lost support, resurfacing addresses surface texture, and bio-remodelling addresses hydration and quality. They are complementary rather than alternatives.

Sensible sequencing avoids doing everything in one appointment. Convention is to allow around two weeks between this and botulinum toxin or resurfacing in the same area, mostly so that any reaction can be attributed to the right treatment.

See skin boosters and polynucleotides for the neighbouring options, which are often confused with this one.

How to judge whether it worked

This is a treatment whose result is genuinely difficult to see in a mirror, because the change is gradual and because you look at your own face every day. Without a reference point, most people conclude either that nothing happened or that everything did, depending on what they expected.

The reference point is a photograph taken under conditions you can repeat: the same room, the same time of day, the same light source in the same position, the same distance, no make-up, and a neutral expression. Take one before the first session and another at around eight weeks after it. That comparison is worth more than any number of clinic images.

What you are looking for is not a change in shape. It is how evenly the skin reflects light, how fine crepiness reads at the cheek and under the eye, and how the skin looks late in the day rather than first thing in the morning. If none of that has changed by eight weeks, the treatment has not worked for you, and the correct response is a conversation about whether your concern was ever a skin quality problem rather than a booking for a third session.

Common questions

Is Profhilo a filler?

Not in the usual sense. It is designed to spread through tissue and improve skin quality rather than to stay in place and create shape.

How many sessions do I need?

The standard protocol is two, four weeks apart, then maintenance at around six months.

When will I see a result?

Gradually, with the meaningful change usually assessed around eight weeks after the first session.

Will it lift my face?

No. It improves skin quality and firmness. Significant laxity needs a different treatment.

Can it be used on the neck?

Yes, and the neck is one of the areas where it is most useful, because resurfacing there carries more risk and heals more slowly.

Does it hurt?

A small number of injection points, each briefly stinging. Most people find it very tolerable and no numbing is usually needed.

Can it be dissolved?

It is hyaluronic acid, so hyaluronidase can be used, though this is rarely necessary because the product is not creating shape.

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